Estimated Average Glucose and Self-Monitored Mean Blood Glucose Are Discordant Estimates of Glycemic Control

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Estimated Average Glucose and Self-Monitored Mean Blood Glucose Are Discordant Estimates of Glycemic Control

OBJECTIVE The A1C-Derived Average Glucose study recommended reporting A1C in estimated average glucose (eAG) equivalents. We compared eAG with self-monitored mean blood glucose (MBG) to determine whether eAG is systematically biased due to biological variation in the relationship between MBG and A1C. RESEARCH DESIGN AND METHODS MBG and A1C were recorded from charts of 202 pediatric type 1 dia...

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eAG bias Estimated average glucose and self-monitored mean blood glucose are discordant estimates of glycemic control Running Title: eAG bias

This is an uncopyedited electronic version of an article accepted for publication in Diabetes Care. The American Diabetes Association, publisher of Diabetes Care, is not responsible for any errors or omissions in this version of the manuscript or any version derived from it by third parties. The definitive publisherauthenticated version will be available in a future issue of Diabetes Care in pr...

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Clinically significant disagreement between mean blood glucose and estimated average glucose in two populations: implications for diabetes management.

BACKGROUND Hemoglobin A1c (HbA1c) is highly correlated with mean blood glucose (MBG) levels and widely used in assessment of diabetes therapy. It has been proposed to report HbA1c in terms of an estimated average glucose (eAG) derived from the population regression of MBG on HbA1c. Pertinent to the clinical utility of eAG would be the degree of agreement between eAG and MBG estimated from multi...

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Glycation is the nonenzymatic addition of sugar to amino groups of proteins. While virtually any protein in the body can be glycated, for convenience and ease of obtaining a sample, glycated hemoglobin is measured in the blood obtained from a patient. Blood glucose concentrations exhibit wide diurnal fluctuations due to food ingestion, exercise, and other factors. In contrast, the concentration...

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ژورنال

عنوان ژورنال: Diabetes Care

سال: 2010

ISSN: 0149-5992,1935-5548

DOI: 10.2337/dc09-1498